What is the deadliest road in Mississippi?

I-55 had the most fatal crashes of any numbered road in Mississippi from 2015 to 2024: 290, with 333 deaths. US 49 was second with 278 and US 61 third with 169. Source: NHTSA's Fatality Analysis Reporting System (FARS).

Which interstate in Mississippi is the most dangerous per mile?

I-10, with 13.5 fatal crashes a year per 100 miles over 2015 to 2024 on 78 miles. That is crashes per mile of road, not per vehicle.

How many fatal crashes in Mississippi happen on numbered roads?

4,177 of 6,385 fatal crashes in Mississippi from 2015 to 2024 (65%) were filed on an interstate, US or state route; the rest were on county roads, city streets and unnamed roads, which are in the state's total but not ranked here.

The deadliest roads in Mississippi

I-55 had the most fatal crashes of any numbered road in Mississippi from 2015 to 2024: 290, with 333 deaths. Over 2022 to 2024 alone, US 49 had the most, 103 against 90 on I-55. The 60 roads listed held 56% of all fatal crashes in Mississippi from 2015 to 2024; 6 are interstates, 14 US routes, 40 state highways.

226 numbered roads in Mississippi recorded a fatal crash in those years; the 60 with 5 or more are ranked below, and 27 have a page of their own. All fatal crashes in Mississippi.

Every numbered road in Mississippi, ranked by fatal crashes

	Road	Kind	Fatal crashes	Deaths	2022 to 2024	Counties with the most
1	I-55	Interstate	290	333	90	Hinds, DeSoto, Madison
2	US 49	US route	278	306	103	Forrest, Harrison, Covington
3	US 61	US route	169	196	41	Bolivar, Tunica, Washington
4	I-20	Interstate	149	172	42	Hinds, Lauderdale, Rankin
5	US 45	US route	140	159	39	Lee, Monroe, Lowndes
6	US 82	US route	136	157	55	Washington, Leflore, Sunflower
7	I-59	Interstate	121	139	36	Pearl River, Jones, Forrest
8	US 98	US route	106	123	33	Lamar, Pike, Marion
9	I-10	Interstate	105	119	40	Jackson, Harrison, Hancock
10	State Highway 15	State highway	101	115	27	Jasper, Neshoba, Jones
11	US 90	US route	95	102	35	Harrison, Jackson, Hancock
12	US 84	US route	81	89	23	Covington, Jones, Wayne
13	US 51	US route	81	88	25	Grenada, Panola, Copiah
14	State Highway 25	State highway	79	91	23	Tishomingo, Oktibbeha, Winston
15	State Highway 35	State highway	71	79	22	Scott, Leake, Marion
16	US 72	US route	68	81	25	Alcorn, Marshall, Benton
17	US 80	US route	68	75	20	Hinds, Rankin, Scott
18	State Highway 16	State highway	67	83	17	Neshoba, Madison, Leake
19	US 278	US route	66	79	15	Lafayette, Pontotoc, Panola
20	State Highway 18	State highway	62	71	23	Hinds, Rankin, Claiborne
21	State Highway 43	State highway	59	64	15	Pearl River, Madison, Attala
22	State Highway 12	State highway	55	71	21	Holmes, Lowndes, Oktibbeha
23	State Highway 63	State highway	54	59	13	George, Jackson, Greene
24	I-22	Interstate	52	61	18	Marshall, Itawamba, Lee
25	State Highway 19	State highway	50	51	15	Lauderdale, Neshoba, Attala
26	State Highway 13	State highway	49	52	17	Jefferson Davis, Marion, Scott
27	State Highway 4	State highway	48	56	13	Tate, Tippah, Benton
28	State Highway 302	State highway	47	49	19	DeSoto, Marshall
29	US 11	US route	46	55	24	Pearl River, Jones, Forrest
30	State Highway 28	State highway	39	45	9	Copiah, Simpson, Jefferson
31	State Highway 7	State highway	39	45	11	Lafayette, Marshall, Yalobusha
32	State Highway 8	State highway	39	45	11	Grenada, Chickasaw, Bolivar
33	US 78	US route	36	41	3	DeSoto, Marshall, Union
34	State Highway 27	State highway	34	40	13	Hinds, Copiah, Warren
35	I-220	Interstate	32	35	11	Hinds, Madison
36	State Highway 178	State highway	32	33	6	Marshall, Lee, DeSoto
37	State Highway 3	State highway	31	35	12	Quitman, Yazoo, Sunflower
38	State Highway 9	State highway	31	34	8	Pontotoc, Calhoun, Choctaw
39	State Highway 145	State highway	30	36	10	Lee, Lauderdale, Clarke
40	State Highway 30	State highway	30	33	8	Union, Lafayette, Prentiss
41	State Highway 42	State highway	29	32	9	Forrest, Jefferson Davis, Lamar
42	State Highway 26	State highway	27	29	5	Pearl River, Stone, George
43	State Highway 53	State highway	25	28	8	Harrison, Pearl River, Hancock
44	State Highway 1	State highway	25	25	9	Washington, Bolivar, Calhoun
45	State Highway 21	State highway	24	25	7	Neshoba, Scott, Kemper
46	State Highway 57	State highway	24	25	6	Jackson, Greene, George
47	State Highway 17	State highway	23	24	6	Holmes, Carroll, Madison
48	State Highway 613	State highway	23	24	9	Jackson, George
49	State Highway 32	State highway	22	23	9	Tallahatchie, Chickasaw, Yalobusha
50	State Highway 24	State highway	21	24	10	Amite, Wilkinson, Pike
51	State Highway 315	State highway	21	22	5	Panola, Yalobusha, Quitman
52	State Highway 14	State highway	19	25	6	Attala, Winston, Noxubee
53	State Highway 309	State highway	19	21	5	Marshall
54	US 45A	US route	19	21	5	Monroe, Clay, Lowndes
55	State Highway 39	State highway	18	20	2	Lauderdale, Kemper
56	State Highway 29	State highway	18	18	6	Perry, Jones, Stone
57	State Highway 6	State highway	15	17	4	Lee, Monroe, Quitman
58	State Highway 50	State highway	15	16	8	Clay, Lowndes
59	State Highway 603	State highway	14	17	2	Hancock
60	State Highway 305	State highway	14	14	4	DeSoto, Tate

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Download every numbered road in Mississippi as CSV. Free to reuse with credit: “Fatal Crash Data, fatalcrashdata.com/deadliest-roads/mississippi/, from NHTSA FARS (2024 Annual Report File).”

Interstates in Mississippi per mile

Fatal crashes a year per 100 miles of road, 2015 to 2024, for interstates with 20 miles or more in Mississippi. Crashes per mile of road, not per vehicle. Mileage from the FHWA Interstate route log.

	Road	Per 100 miles a year	Fatal crashes	Miles
1	I-10	13.5	105	78
2	I-55	10.0	290	289
3	I-20	9.5	149	156
4	I-59	8.2	121	148
5	I-22	4.9	52	107

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Questions about the deadliest roads in Mississippi

What is the deadliest road in Mississippi?: I-55 had the most fatal crashes of any numbered road in Mississippi from 2015 to 2024: 290, with 333 deaths. US 49 was second with 278 and US 61 third with 169. Source: NHTSA's Fatality Analysis Reporting System (FARS).
Which interstate in Mississippi is the most dangerous per mile?: I-10, with 13.5 fatal crashes a year per 100 miles over 2015 to 2024 on 78 miles. That is crashes per mile of road, not per vehicle.
How many fatal crashes in Mississippi happen on numbered roads?: 4,177 of 6,385 fatal crashes in Mississippi from 2015 to 2024 (65%) were filed on an interstate, US or state route; the rest were on county roads, city streets and unnamed roads, which are in the state's total but not ranked here.

Where the Mississippi road numbers come from

Counted from NHTSA's Fatality Analysis Reporting System, 2024 Annual Report File: every fatal crash filed on a numbered interstate, US or state route in Mississippi, read from the road name NHTSA filed, with ramps, frontage and service roads left out. A road gets its own page with 15 or more fatal crashes from 2022 to 2024. The full method.