Fatal Crash Data

US 378 in South Carolina: fatal crashes

From 2015 to 2024, 90 fatal crashes on US 378 in South Carolina killed 105 people, the 18th most of any numbered road in South Carolina. In 2024 there were 7 fatal crashes and 8 deaths on the road.

An US route running through 11 counties of South Carolina. All fatal crashes in South Carolina.

Deaths on US 378 in South Carolina by year

10201620182020202220242020: 162024: 8
YearFatal crashesDeaths
2015812
201666
20171010
201844
20191315
20201416
202167
20221113
20231114
202478

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Where on US 378 in South Carolina: the counties with the most fatal crashes

Lexington County had the most fatal crashes on US 378 from 2015 to 2024: 22, with 26 deaths. Counties are listed from 5 fatal crashes.

County20242015 to 2024Deaths
1Lexington12226
2Sumter32223
3Florence01519
4Horry0911
5Marion159

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

When fatal crashes happen on US 378 in South Carolina

Too few crashes to name a heaviest slot. The grid shows the shares; a share is only given over 20 crashes.

Share of fatal crashes in US 378 in South Carolina by weekday and time of day, 2015 to 2024, in percent
Midnight to 44 to 8 am8 to noonNoon to 44 to 8 pm8 to midnight
Sun4.4 percent, 4 fatal crashes1.1 percent, 1 fatal crashes1.1 percent, 1 fatal crashes2.2 percent, 2 fatal crashes5.6 percent, 5 fatal crashes5.6 percent, 5 fatal crashes
Mon0.0 percent, 0 fatal crashes3.3 percent, 3 fatal crashes1.1 percent, 1 fatal crashes2.2 percent, 2 fatal crashes1.1 percent, 1 fatal crashes1.1 percent, 1 fatal crashes
Tue1.1 percent, 1 fatal crashes3.3 percent, 3 fatal crashes0.0 percent, 0 fatal crashes2.2 percent, 2 fatal crashes3.3 percent, 3 fatal crashes2.2 percent, 2 fatal crashes
Wed0.0 percent, 0 fatal crashes3.3 percent, 3 fatal crashes1.1 percent, 1 fatal crashes2.2 percent, 2 fatal crashes2.2 percent, 2 fatal crashes1.1 percent, 1 fatal crashes
Thu0.0 percent, 0 fatal crashes0.0 percent, 0 fatal crashes1.1 percent, 1 fatal crashes3.3 percent, 3 fatal crashes5.6 percent, 5 fatal crashes2.2 percent, 2 fatal crashes
Fri2.2 percent, 2 fatal crashes3.3 percent, 3 fatal crashes2.2 percent, 2 fatal crashes5.6 percent, 5 fatal crashes2.2 percent, 2 fatal crashes3.3 percent, 3 fatal crashes
Sat2.2 percent, 2 fatal crashes4.4 percent, 4 fatal crashes2.2 percent, 2 fatal crashes0.0 percent, 0 fatal crashes1.1 percent, 1 fatal crashes7.8 percent, 7 fatal crashes

By hour

By month

  • Jan5.6%
  • Feb5.6%
  • Mar5.6%
  • Apr10.0%
  • May5.6%
  • Jun14.4%
  • Jul11.1%
  • Aug14.4%
  • Sep4.4%
  • Oct7.8%
  • Nov10.0%
  • Dec5.6%

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

What fatal crashes on US 378 in South Carolina first hit

First harmful eventFatal crashesShare
Collision with another vehicle4954%
Pedestrian1618%
Fixed object (tree, pole, barrier, ditch)1314%
Rollover77.8%
Cyclist33.3%
Other22.2%
Parked vehicle00.0%
Not reported00.0%

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

How fatal crashes on US 378 in South Carolina compare with the state

Shares of fatal crashes from 2015 to 2024, against the share across all of South Carolina. A share is only given over 20 crashes.

US 378South Carolina
On rural stretches69%59%above the South Carolina share
At or near an intersection31%20%above the South Carolina share
In the dark, road unlit43%37%above the South Carolina share
A drinking driver22%32%below the South Carolina share
Speeding30%40%below the South Carolina share
Occupants killed unbelted39%53%below the South Carolina share
Hit-and-run3.3%4.2%about the same as the South Carolina share
A motorcycle involved14%16%below the South Carolina share
Pedestrians among the dead15%16%about the same as the South Carolina share

Source: NHTSA Fatality Analysis Reporting System (FARS), 2024 Annual Report File (released April 2026, subject to revision). How we count

Other roads in South Carolina with a page

All fatal crashes in South Carolina, with every road ranked.

Where the US 378 numbers come from

Counted from NHTSA's Fatality Analysis Reporting System, 2024 Annual Report File: every fatal crash whose road NHTSA filed as US 378 in South Carolina (filed under 15 spellings, such as "US- 378 MYRTLE BEACH HWY", "US-378", "US-378 BROAD STREET", "US-378 COLUMBIA HWY"). Ramps, frontage and service roads are left out. A fatal crash is one in which someone died within 30 days. The full method.